Conventional / global / constitutive KO
●2 Models Available
READY TO SHIP!
LIVE · SPERM
Hnrnpa2b1 Conditional Knockout, Knockout mouse models
Browse 2 Hnrnpa2b1 mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Hnrnpa2b1 conditional knockout mouse, Hnrnpa2b1 knockout mouse. Request a quote within 24 hours.
Why model Hnrnpa2b1
Alternative splicing of exon 2 in Hnrnpa2b1, the mouse ortholog of human HNRNPA2B1, produces the A2 and B1 isoforms of a nuclear RNA-binding protein that pairs two RRM domains with a glycine-rich prion-like domain. A2 binds the A2 response element to transport myelin basic protein transcripts along oligodendrocyte processes, functions as a nuclear reader of N6-methyladenosine that shapes splicing and primary microRNA processing, and phase separates into transport granules whose material state is tuned by arginine methylation. Prion-like domain mutations such as D290V steepen the fibrillization trajectory and cause multisystem proteinopathy with ALS, so disease knockins capture the aggregation mechanism that deletion does not. Conditional alleles are preferable given the broad requirement for this protein in splicing and myelination, and pairing with Cnp-Cre or neuronal drivers localizes the phenotype. Hnrnpa1 shares many binding sites, so compound genetics and transcriptome-wide splicing readouts should be planned alongside the primary allele.
What Hnrnpa2b1 mouse models are available?
ingenious targeting laboratory offers 2 distinct Hnrnpa2b1 (HNRNPA2B1) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Hnrnpa2b1 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Hnrnpa2b1 allele types
Knockout, conditional, knockin, humanized, and related paths for Hnrnpa2b1 (human HNRNPA2B1). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Hnrnpa2b1 catalog models
2 Hnrnpa2b1 lines with QC documentation and technical support. Hnrnpa2b1 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Hnrnpa2b1-Flox
CKOCKO
These mice carry loxP sites flanking exon2-6 of Hnrnpa2b1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hnrnpa2b1 gene.
LiveCKO 205193 - Order
Hnrnpa2b1-KO
KOKO
exon 2-6 of Hnrnpa2b1 gene was deleted to generate Hnrnpa2b1 knockout mice.
Sperm CryopreservedKO 226355
Looking for a Hnrnpa2b1 mouse model?
We have 2 Hnrnpa2b1 models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Hnrnpa2b1 Mouse Model Types
A Hnrnpa2b1 knockout mouse has the Hnrnpa2b1 gene permanently inactivated, enabling loss of function studies. A Hnrnpa2b1 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Hnrnpa2b1, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Hnrnpa2b1 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the Hnrnpa2b1 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.