Conventional / global / constitutive KO
●2 Models Available
READY TO SHIP!
LIVE · IN PRODUCTION
Kcnj15 Conditional Knockout, Knockout mouse models
Browse 2 Kcnj15 mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Kcnj15 conditional knockout mouse, Kcnj15 knockout mouse. Request a quote within 24 hours.
Why model Kcnj15
Kcnj15, the mouse ortholog of human KCNJ15, encodes Kir4.2, an inwardly rectifying potassium channel closely related to Kir4.1 that assembles as a homotetramer or, more commonly in native tissue, as a heteromer with Kir5.1 encoded by Kcnj16, an arrangement that confers steep sensitivity to intracellular pH and carbon dioxide. Kir4.2 is expressed on the basolateral membrane of proximal tubule and other kidney segments, in liver, pancreas, and lung, and in restricted neural populations, where it contributes to potassium recycling that supports electrogenic transport and to acid-base sensing. The gene lies within the Down syndrome critical region on human chromosome 21 and has been linked to glucose handling and diabetic nephropathy risk. Conditional nulls with segment-restricted Cre drivers are the appropriate design for transport phenotypes, while pH-sensing residue knockins test the chemosensory hypothesis directly. Because Kir4.1 covers overlapping territory in some tissues, quantify heteromer composition rather than assuming a clean single-subunit loss.
What Kcnj15 mouse models are available?
ingenious targeting laboratory offers 2 distinct Kcnj15 (KCNJ15) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Kcnj15 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Kcnj15 allele types
Knockout, conditional, knockin, humanized, and related paths for Kcnj15 (human KCNJ15). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Kcnj15 catalog models
2 Kcnj15 lines with QC documentation and technical support. Kcnj15 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Kcnj15-Flox
CKOCKO
These mice carry loxP sites flanking exon 4 of Kcnj15 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Kcnj15 gene.
In production — inquireCKO 262067 - Order
Kcnj15-KO
KOKO
Exon 4 of Kcnj15 gene was deleted to generate Kcnj15 knockout mice.
LiveKO 200284
Looking for a Kcnj15 mouse model?
We have 2 Kcnj15 models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Kcnj15 Mouse Model Types
A Kcnj15 knockout mouse has the Kcnj15 gene permanently inactivated, enabling loss of function studies. A Kcnj15 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Kcnj15, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Kcnj15 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the Kcnj15 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.