Conventional / global / constitutive KO
●2 Models Available
Rictor Conditional Knockout, Knockout mouse models
Browse 2 Rictor mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Rictor conditional knockout mouse, Rictor knockout mouse. Contact us for availability and fast turnaround.
Why model Rictor
Defining mTOR complex 2, Rictor is the ortholog of human RICTOR and encodes a large scaffold that, with mSIN1 and mLST8, confers substrate specificity for the hydrophobic motifs of AKT Ser473, SGK1 and conventional PKC isoforms, alongside a turn motif phosphorylation that stabilizes nascent AGC kinases. Unlike mTORC1, the complex resists acute rapamycin but is disassembled by prolonged exposure, which makes genetic ablation the only clean way to separate mTORC2 from pharmacologically confounded mTORC1 readouts. Germline deletion is embryonic lethal at midgestation, so conditional nulls with tissue-restricted Cre drivers are required, and running matched Rptor conditional cohorts is the standard way to attribute a phenotype to one complex rather than to the kinase itself. No paralog substitutes, though the accessory subunits Protor-1 and Protor-2 tune substrate selection, so interpret residual SGK1 signaling carefully when the endpoint is renal sodium handling or metabolic control.
What Rictor mouse models are available?
ingenious targeting laboratory offers 2 distinct Rictor (RICTOR) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Rictor model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Rictor allele types
Knockout, conditional, knockin, humanized, and related paths for Rictor (human RICTOR). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Rictor catalog models
2 Rictor lines with QC documentation and technical support. Rictor floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Rictor mouse model?
We have 2 Rictor models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Rictor Mouse Model Types
A Rictor knockout mouse has the Rictor gene permanently inactivated, enabling loss of function studies. A Rictor conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Rictor, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Rictor organized by modification type. Each URL is indexable and matches common search patterns.