Conventional / global / constitutive KO
●4 Models Available
READY TO SHIP!
LIVE · SPERM · EMBRYO
Slc17a7 Knockin mouse models
Browse 4 Slc17a7 mouse models including knockin variants — in stock and ready to ship from ingenious targeting laboratory. Request a quote within 24 hours.
Why model Slc17a7
Cortical and hippocampal glutamatergic terminals depend on Slc17a7, the mouse ortholog of human SLC17A7, encoding VGLUT1, the SLC17 family vesicular transporter that fills synaptic vesicles using the proton motive force generated by the vacuolar ATPase and that additionally recruits endophilin A1 through its C-terminal polyproline region to slow vesicle endocytosis and shape release probability during sustained activity. VGLUT1 defines telencephalic excitatory identity and is developmentally exchanged for VGLUT2 at many synapses. Homozygous nulls survive birth but decline sharply after the third postnatal week with blindness, ataxia, and death, reflecting that developmental switch, so conditional alleles are strongly preferred for adult circuit work. Knockin Cre or reporter alleles at the locus provide clean access to cortical excitatory populations. Because VGLUT2 partially substitutes at a subset of synapses during early development, interpret quantal size and vesicle filling phenotypes with that transient overlap in mind and select region-specific Cre drivers accordingly.
What Slc17a7 mouse models are available?
ingenious targeting laboratory offers 4 distinct Slc17a7 (SLC17A7) catalog mouse models, featuring knockin. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 4 Ready Catalog Lines | Conditional Knockout (cKO) on request |
| Custom Model Generation | Constitutive Knockout (KO) on request |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Slc17a7 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Slc17a7 allele types
Knockout, conditional, knockin, humanized, and related paths for Slc17a7 (human SLC17A7). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Slc17a7 catalog models
4 Slc17a7 lines with QC documentation and technical support.
- Order
Slc17a7-IRES-Cre
KICre/Dre Toolbox
A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.
LiveKI 200086 - Order
Slc17a7-IRES-Flp
KICre/Dre Toolbox
The IRES-Flp expression cassette was knocked into the Slc17a7 gene stop codon site.
Sperm CryopreservedKI 241604 - Order
Slc17a7-2A-tdTomato
KIFluorescent Model
2A-tdTomato expression cassette was knocked into the Slc17a7 gene.
Embryo CryopreservedKI 210126 - Order
Slc17a7-2A-TagBFP
KIFluorescent Model
2A-TagBFP expression cassette was knocked into the Slc17a7 gene stop codon site.
Sperm CryopreservedKI 220180
Looking for a Slc17a7 mouse model?
We have 4 Slc17a7 models in stock — including Knockin types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
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Models Available
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Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Slc17a7 Mouse Model Types
Slc17a7 knockin models carry a precisely inserted sequence at the Slc17a7 locus, useful for reporter, tag, or humanization studies.
Modifications available
Jump to catalog backed pages for Slc17a7 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the Slc17a7 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.