Conventional / global / constitutive KO
●3 Models Available
Mmp9 Conditional Knockout, Knockout mouse models
Browse 3 Mmp9 mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Mmp9 conditional knockout mouse, Mmp9 knockout mouse. Contact us for availability and fast turnaround.
Why model Mmp9
Encoding gelatinase B, Mmp9 corresponds to human MMP9 and is distinguished by a fibronectin type II insert that grips gelatin and by a heavily O-glycosylated linker preceding the hemopexin domain, which mediates association with TIMP1 and with neutrophil specific storage that allows immediate release from preformed tertiary granules without new transcription. Substrates include type IV and V collagen, elastin, and several chemokines, and its best validated in vivo function is liberating matrix sequestered VEGF to trigger the angiogenic switch, a role established genetically in islet tumorigenesis models. Nulls are viable with delayed growth plate ossification and reduced neutrophil dependent tissue injury, and compensation by Mmp2 means gelatinolytic phenotypes often require both alleles. Because bone marrow derived cells supply most of the enzyme, conditional deletion or reciprocal marrow transplantation is what separates hematopoietic from stromal sources, catalytically dead knockins isolate proteolysis, and humanization supports selective inhibitor programs where broad spectrum compounds failed.
What Mmp9 mouse models are available?
ingenious targeting laboratory offers 3 distinct Mmp9 (MMP9) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 3 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Mmp9 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Mmp9 allele types
Knockout, conditional, knockin, humanized, and related paths for Mmp9 (human MMP9). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Mmp9 catalog models
3 Mmp9 lines with QC documentation and technical support. Mmp9 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Mmp9 mouse model?
We have 3 Mmp9 models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model3
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Mmp9 Mouse Model Types
A Mmp9 knockout mouse has the Mmp9 gene permanently inactivated, enabling loss of function studies. A Mmp9 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Mmp9, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Mmp9 organized by modification type. Each URL is indexable and matches common search patterns.