Conventional / global / constitutive KO
●2 Models Available
READY TO SHIP!
EMBRYO · IN PRODUCTION
Uqcrc1 Conditional Knockout, Knockout mouse models
Browse 2 Uqcrc1 mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Uqcrc1 conditional knockout mouse, Uqcrc1 knockout mouse. Request a quote within 24 hours.
Why model Uqcrc1
Uqcrc1 is the mouse ortholog of human UQCRC1 and encodes core protein 1 of complex III, a large matrix-facing subunit that, with core protein 2, adopts a mitochondrial processing peptidase-like fold and forms the structural platform onto which cytochrome b, cytochrome c1 and the Rieske protein assemble in the dimeric bc1 enzyme. These core subunits carry no redox center but are required for holoenzyme stability and for processing events during maturation of the Rieske subunit presequence, so their reduction destabilizes the entire complex and lowers ubiquinol to cytochrome c oxidoreductase flux. Human variants have been linked to complex III deficiency and, separately, reported in familial parkinsonism with dopaminergic vulnerability, making both a conditional null with dopaminergic Cre drivers and a patient-matched missense knockin defensible depending on whether bioenergetic failure or neurodegeneration is the question. Core protein 2 does not substitute. Select blue native assembly, respirometry and dopaminergic histology as paired endpoints.
What Uqcrc1 mouse models are available?
ingenious targeting laboratory offers 2 distinct Uqcrc1 (UQCRC1) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Uqcrc1 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Uqcrc1 allele types
Knockout, conditional, knockin, humanized, and related paths for Uqcrc1 (human UQCRC1). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Uqcrc1 catalog models
2 Uqcrc1 lines with QC documentation and technical support. Uqcrc1 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Uqcrc1-Flox
CKOCKO
These mice carry loxP sites flanking exon 3-4 of Uqcrc1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Uqcrc1 gene.
In production — inquireCKO 253687 - Order
Uqcrc1-KO
KOKO
Exon 3-4 of Uqcrc1 gene was deleted to generate Uqcrc1 knockout mice.
F0 Embryo CryopreservedKO 190896
Looking for a Uqcrc1 mouse model?
We have 2 Uqcrc1 models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Uqcrc1 Mouse Model Types
A Uqcrc1 knockout mouse has the Uqcrc1 gene permanently inactivated, enabling loss of function studies. A Uqcrc1 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Uqcrc1, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Uqcrc1 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the Uqcrc1 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.