Conventional / global / constitutive KO
●6 Models Available
Ifng Conditional Knockout, Knockin, Knockout mouse models
Browse 6 Ifng mouse models including conditional knockout, knockin, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Ifng conditional knockout mouse, Ifng knockin mouse, Ifng knockout mouse. Request a quote within 24 hours.
Why model Ifng
Interferon gamma, encoded by Ifng, is the mouse ortholog of human IFNG and the only type II interferon, a homodimeric cytokine that clusters IFNGR1 with IFNGR2, activates JAK1 and JAK2, and drives STAT1 homodimers onto gamma activated sequences to induce CIITA and MHC class II, immunoproteasome subunits, CXCL9 and CXCL10, and nitric oxide synthase in primed macrophages. Its sources are Th1 cells, NK cells, ILC1s, and cytotoxic lymphocytes, and human loss-of-function lesions in this pathway cause Mendelian susceptibility to mycobacterial disease, whereas excess drives hemophagocytic pathology. Allele choices diverge sharply: a conditional null asks whether a given lymphocyte lineage supplies the cytokine, a knockin reporter reads transcription without perturbing it, and humanization supports emapalumab-class neutralization studies. Pair the Ifng flox with Cd4-Cre, Cd8-Cre, or Ncr1-Cre rather than germline deletion when the goal is attributing the cellular source rather than ablating the axis entirely.
What Ifng mouse models are available?
ingenious targeting laboratory offers 6 distinct Ifng (IFNG) catalog mouse models, featuring conditional knockout, standard knockout, and knockin. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 6 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Ifng model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Ifng allele types
Knockout, conditional, knockin, humanized, and related paths for Ifng (human IFNG). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Ifng catalog models
6 Ifng lines with QC documentation and technical support. Ifng floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Ifng-Flox
Conditional KnockoutKO/CKO mice
sperm cryopreservationCKO 220246 - Order
Ifng-del(162bp)
Knockinpoint mutantion mice
sperm cryopreservationKI 210223 - Order
Ifng-2A-Luc
Knockinfluorescent mouse
sperm cryopreservationKI 233526 - Order
Ifng-Venus-Luc
Knockinfluorescent mouse, disease model mice
embryo cryopreservationKI 18041 - Order
Ifng-KO(3)
KnockoutKO/CKO mice
sperm cryopreservationKO 232796 - Order
Ifng-KO
KnockoutKO/CKO mice, disease model mice
liveKO 200723
Looking for a Ifng mouse model?
We have 6 Ifng models in stock — including Conditional Knockout, Knockin, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model6
Models Available
3
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Ifng Mouse Model Types
A Ifng knockout mouse has the Ifng gene permanently inactivated, enabling loss of function studies. A Ifng conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Ifng, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints. Ifng knockin models carry a precisely inserted sequence at the Ifng locus, useful for reporter, tag, or humanization studies.
Modifications available
Jump to catalog backed pages for Ifng organized by modification type. Each URL is indexable and matches common search patterns.