"A better model is within reach."

Conditional Knockout

CXCR4 Conditional Knockout Mouse

CXCR4 Conditional Knockout Mouse

Why Is the Development of CXCR4 Conditional Knockout Mice So Important? CXCR4 conditional knockout mice have become extremely popular due to the many practical uses that understanding the Cxcr4 receptor can bring. Chemokines – and most especially the chemokine CXCL12 and its receptor CXCR4– are viewed as some of the most crucial pieces of genetic […]

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CRISPR Cas9 Conditional Knockout Mouse Model

CRISPR Cas9 Conditional Knockout Mouse Model

The Versatility of CRISPR Cas9 – Conditional Knockout Mouse Model Solutions When considering the use of CRISPR Cas9, conditional knockout mouse model development can be greatly improved. The CRISPR Cas9 tool has become extremely popular due to its ease and convenience, as well as the ability for researchers to use it for a wide variety […]

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Conditional Knockout Mouse Protocol

Conditional Knockout Mouse Protocol

Understanding the Conditional Knockout Mouse Protocol and What It Means to Modern Genetics Setting up a conditional knockout mouse protocol can be a challenging prospect, but it’s also very useful for modern genetic research. Knockout mice have helped scientists and genetic researchers find out more about various genes and understanding the mammalian genome at its […]

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Conditional Knockout Mouse and Global Knockout Mouse

Conditional Knockout Mouse and Global Knockout Mouse

Conditional Knockout Mouse and Global Knockout Mouse Models – What Is the Difference? Whether we’re on the topic of regular or humanized mice, the differences between conditional knockout mouse and global knockout mouse models are extremely important. While one is easier to obtain and has to do with the deletion of a specific gene at […]

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Conditional Gene Knockout Mouse

Conditional Gene Knockout Mouse

Conditional Gene Knockout Mouse Models and Their Invaluable Contribution to Genetic Research The more we know about conditional gene knockout mouse models, the greater the chance that future researchers can use studies and tests done on these laboratory mice to discover invaluable breakthroughs in genetic research and medicine. As science progresses, systems based on basic […]

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Cre-Lox Facts

cre-lox

6 Facts You May Not Know About Cre-Lox By Richard Row, PhD The basics of conditional knockout mice are familiar to any researcher who uses mouse models, even if this model type isn’t yet a part of your research. Using the Cre-lox system in an experiment seems simple: two lines are crossed, one with tissue-specific […]

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A Conditional Knockout That Took Research Further

conditional knockout model

The Right Myopathy Model After years of work in in vitro systems and cultured cells your research may reach a point where an animal model is required. This major transition requires a new mindset, and consideration of factors that didn’t previously affect experiments. When evaluating genetically modified animal models each stage of their life must […]

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