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Explore 14,774+ genetically engineered mouse and rat models

Found 25+ models matching “point mutation”

Gene	Model	Type	Category	Status	Catalog
Mtm1	Mtm1-C375S	KI	Point Mutation	DEVELOPING	KI 264121	Inquire
These mice carry a C375S mutation of Mtm1 gene.
Mtm1	Mtm1-R69C	KI	Point Mutation	DEVELOPING	KI 264120	Inquire
These mice carry a R69C mutation of Mtm1 gene.
hMECP2	hMECP2-T158M	HU	Target-Humanized, Point Mutation	DEVELOPING	HU 263634	Inquire
The endogenous mouse Mecp2 gene was replaced by human MECP2 gene.
Cdk3	Cdk3-561DM	KI	Point Mutation	DEVELOPING	KI 263581	Inquire
These mice carry a X187W mutation of Cdk3 gene.
Col1a2	Col1a2-G706C	KI	Point Mutation	IN PRODUCTION	KI 263058	Inquire
These mice carry a G706C mutation of Col1a2 gene.
huHSC	huHSC-(Kit-V831M M-NSG)	HU	Immunodeficient, Point Mutation	LIVE	HU 263011	Inquire
iTL constructed Kit-V831M(NMG) mice by replacing valine (V) with methionine (M) at amino acid position 831 of the mouse Kit gene. Based on this model, human CD34+ HSCs were transplanted into these mice.
Col1a1	Col1a1-G516C	KI	Point Mutation	IN PRODUCTION	KI 262985	Inquire
These mice carry a G516C mutation of Col1a1 gene.
Ifitm5	Ifitm5-c.-14C>T	KI	Point Mutation	DEVELOPING	KI 262983	Inquire
These mice carry a c.-14C>T mutation of Ifitm5 gene.
R26	R26-CAG-LSL-hINSR-D734A	KI	Overexpression, Target-Humanized, Point Mutation	DEVELOPING	KI 262953	Inquire
CAG-LSL-Kozak-hINSR-D734A-WPRE-pA expression cassette was knocked into the the Rosa26 locus.
Pln	Pln-R14del	KI	Point Mutation	IN PRODUCTION	KI 262051	Inquire
These mice carry a R14del mutation of Pln gene.
Pkd1	Pkd1-R3269C	KI	Point Mutation	DEVELOPING	KI 261794	Inquire
These mice carry a R3269C mutation of Pkd1 gene.
Pkd1	Pkd1-L2811P	KI	Point Mutation	DEVELOPING	KI 261705	Inquire
These mice carry a L2811P mutation of Pkd1 gene. This site corresponds to the human gene PKD1 (Gene ID: 5310) p.L2816P.
Rpl36	Rpl36-C48A	KI	Point Mutation	IN PRODUCTION	KI 261621	Inquire
These mice carry a C48A mutation of Rpl36 gene.
Kit	Kit-V831M/hIL3-hCSF2-Tg(M-NSG)	XA	Point Mutation, Target-Humanized, Immunodeficient, Random Transgenic	LIVE	XA 261535	Inquire
The Kit-V831M(NMG) (KI 242813) was crossed with hIL3-hCSF2-Tg(NMG)(KI 215006) to generate Kit-V831M(NMG)/hIL3-hCSF2-Tg(NMG) mice.
Uba1	Uba1-M41L	KI	Point Mutation	DEVELOPING	KI 261500	Inquire
These mice carry a M41L mutation of Uba1 gene.
Apoe	Apoe-KO(2)/Crbn-I391V	XA	KO, Point Mutation	DEVELOPING	XA 261456	Inquire
The Crbn-I391V (KI 200331) was crossed with Apoe-KO(2)(KO 190565) to generate Crbn-I391V/Apoe-KO(2) mice.
Bmpr2	Bmpr2-R899*	KI	Point Mutation	DEVELOPING	KI 261448	Inquire
These mice carry a R899* mutation of Bmpr2 gene.
Vrk1	Vrk1-759bp VRK1:c.1159+599A>G	KI	Point Mutation	IN PRODUCTION	KI 260988	Inquire
The 759bp VRK1:c.1159+599A>G expression cassette was knocked into the Vrk1 gene locus.
Jak2	Jak2-Flox-V617F/Vav1-2A-Cre	XA	Point Mutation, Cre/Dre Toolbox, Disease Model	DEVELOPING	XA 260618	Inquire
The Jak2-Flox-V617F (KI 210367) was crossed with Vav1-2A-Cre(KI 233228) to generate Jak2-Flox-V617F/Vav1-2A-Cre mice.
Trpm2	Trpm2-W742A	KI	Point Mutation	LIVE	KI 254279	Inquire
These mice carry a W742A mutation of Trpm2 gene.
Pkd1	Pkd1-R2216W	KI	Point Mutation	IN PRODUCTION	KI 253947	Inquire
These mice carry a R2216W mutation of Pkd1 gene.
Unc93b1	Unc93b1-R95L	KI	Point Mutation	LIVE	KI 253899	Inquire
These mice carry a R95L mutation of Unc93b1 gene.
H11	H11-CAG-LSL-Myc*T58A-IRES-Luc/Trp53-Flox	XA	CKO, Point Mutation, Overexpression, Fluorescent Model	SPERM	XA 253651	Inquire
Based on Trp53-Flox (CKO 18005), the CAG-LSL-Kozak-MycT58A-IRES-Luciferase-WPRE-pA sequence was inserted into the Igs2 locus of mice, resulting in the generation of H11-CAG-LSL-MycT58A-IRES-Luciferase-WPRE-pA mice with dual gene modifications of Trp53-Flox.
H11	H11-CAG-LSL-Myc*T58A-IRES-Luc	KI	Point Mutation, Overexpression, Fluorescent Model	SPERM	KI 253650	Inquire
CAG-LSL-Kozak-Myc*T58A-IRES-Luciferase-WPRE-pA expression cassette was knocked into the the Igs2 locus.
Sting1	Sting1-I199N	KI	Point Mutation	LIVE	KI 253568	Inquire
These mice carry a I199N mutation of Sting1 gene.

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