Conventional / global / constitutive KO
●1 Model Available
READY TO SHIP!
DEVELOPING
Cox7b Conditional Knockout mouse model
Browse 1 Cox7b mouse model including conditional knockout variants from ingenious targeting laboratory. Contact us for availability and fast turnaround.
Why model Cox7b
Cox7b, the mouse ortholog of human COX7B, encodes a small nuclear encoded transmembrane subunit of cytochrome c oxidase incorporated into the late assembly module that completes the shell surrounding the catalytic core, and the gene is X-linked in both species. Human COX7B mutations cause microphthalmia with linear skin defects, an X-linked dominant disorder with male lethality in which skewed X inactivation in females produces mosaic complex IV deficiency, biology that makes X-linked mosaicism itself the experimental variable. Design therefore differs from autosomal COX genes: heterozygous females model mosaic deficiency and developmental patterning defects, while conditional deletion in males tests absolute tissue requirement without whole embryo loss. No paralog substitutes for 7B in somatic tissues. Use Rosa26-CreER, Nes-Cre, or Krt14-Cre depending on whether skin, eye, or nervous system is the endpoint, then read COX histochemistry, clonal patch analysis, complex IV activity, and blue native assembly profiles.
What Cox7b mouse models are available?
ingenious targeting laboratory offers 1 distinct Cox7b (COX7B) catalog mouse model, featuring conditional knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 1 Ready Catalog Line | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) on request |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Cox7b model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Cox7b allele types
Knockout, conditional, knockin, humanized, and related paths for Cox7b (human COX7B). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Cox7b catalog models
1 Cox7b line with QC documentation and technical support. Cox7b floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Cox7b-Flox
CKOCKO
These mice carry loxP sites flanking exon2 of Cox7b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cox7b gene.
In DevelopmentCKO 263367
Looking for a Cox7b mouse model?
We have 1 Cox7b model available — including Conditional Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
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Models Available
1
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Cox7b Mouse Model Types
A Cox7b conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Cox7b, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Cox7b organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ITL
Send the Cox7b line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.