Conventional / global / constitutive KO
●2 Models Available
Ndufa3 Conditional Knockout, Knockout mouse models
Browse 2 Ndufa3 mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Ndufa3 conditional knockout mouse, Ndufa3 knockout mouse. Request a quote within 24 hours.
Why model Ndufa3
Human NDUFA3 corresponds to mouse Ndufa3, encoding the small B9 subunit that inserts into the membrane arm of complex I close to the mtDNA-encoded ND1 subunit, where it participates in the earliest membrane arm assembly module and helps stabilize the region forming the quinone-binding interface. Compared with better characterized accessory subunits, human pathogenic variants are rare, so its biology rests largely on assembly studies showing that loss impairs formation of the ND1-containing intermediate and lowers mature holoenzyme, producing an isolated complex I defect without affecting other respiratory complexes. Given this, a constitutive or conditional null is the informative first allele, and inducible deletion in adult tissues distinguishes developmental from maintenance requirements, while a humanized knockin becomes valuable when candidate variants of uncertain significance need functional adjudication. No paralogous subunit substitutes. Pair the allele with endpoints tracking assembly intermediates by BN-PAGE and complexome profiling, alongside rotenone-sensitive oxygen consumption, ATP synthesis rates, and tissue markers of energetic stress.
What Ndufa3 mouse models are available?
ingenious targeting laboratory offers 2 distinct Ndufa3 (NDUFA3) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Ndufa3 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
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Ndufa3 allele types
Knockout, conditional, knockin, humanized, and related paths for Ndufa3 (human NDUFA3). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Ndufa3 catalog models
2 Ndufa3 lines with QC documentation and technical support. Ndufa3 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Ndufa3 mouse model?
We have 2 Ndufa3 models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Ndufa3 Mouse Model Types
A Ndufa3 knockout mouse has the Ndufa3 gene permanently inactivated, enabling loss of function studies. A Ndufa3 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Ndufa3, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Ndufa3 organized by modification type. Each URL is indexable and matches common search patterns.