Conventional / global / constitutive KO
●2 Models Available
READY TO SHIP!
SPERM
Ndufa3 Conditional Knockout, Knockout mouse models
Browse 2 Ndufa3 mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Ndufa3 conditional knockout mouse, Ndufa3 knockout mouse. Contact us for availability and fast turnaround.
Why model Ndufa3
Human NDUFA3 corresponds to mouse Ndufa3, encoding the small B9 subunit that inserts into the membrane arm of complex I close to the mtDNA-encoded ND1 subunit, where it participates in the earliest membrane arm assembly module and helps stabilize the region forming the quinone-binding interface. Compared with better characterized accessory subunits, human pathogenic variants are rare, so its biology rests largely on assembly studies showing that loss impairs formation of the ND1-containing intermediate and lowers mature holoenzyme, producing an isolated complex I defect without affecting other respiratory complexes. Given this, a constitutive or conditional null is the informative first allele, and inducible deletion in adult tissues distinguishes developmental from maintenance requirements, while a humanized knockin becomes valuable when candidate variants of uncertain significance need functional adjudication. No paralogous subunit substitutes. Pair the allele with endpoints tracking assembly intermediates by BN-PAGE and complexome profiling, alongside rotenone-sensitive oxygen consumption, ATP synthesis rates, and tissue markers of energetic stress.
What Ndufa3 mouse models are available?
ingenious targeting laboratory offers 2 distinct Ndufa3 (NDUFA3) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Ndufa3 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Ndufa3 allele types
Knockout, conditional, knockin, humanized, and related paths for Ndufa3 (human NDUFA3). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Ndufa3 catalog models
2 Ndufa3 lines with QC documentation and technical support. Ndufa3 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Ndufa3-Flox
CKOCKO
These mice carry loxP sites flanking exon 3-4 of Ndufa3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ndufa3 gene.
Sperm CryopreservedCKO 251654 - Order
Ndufa3-KO
KOKO
The exon 3-4 of Ndufa3 gene was deleted to generate Ndufa3 knockout mouse.
Sperm CryopreservedKO 253244
Looking for a Ndufa3 mouse model?
We have 2 Ndufa3 models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Ndufa3 Mouse Model Types
A Ndufa3 knockout mouse has the Ndufa3 gene permanently inactivated, enabling loss of function studies. A Ndufa3 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Ndufa3, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Ndufa3 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ingenious targeting laboratory
Send the Ndufa3 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.