Conventional / global / constitutive KO
●2 Models Available
READY TO SHIP!
DEVELOPING · IN PRODUCTION
Cox7c Conditional Knockout, Knockout mouse models
Browse 2 Cox7c mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Cox7c conditional knockout mouse, Cox7c knockout mouse. Request a quote within 24 hours.
Why model Cox7c
Cox7c, ortholog of human COX7C, encodes one of the smallest nuclear encoded subunits of cytochrome c oxidase, a single transmembrane helix added with subunits 6C and 8A during the final assembly module that seals the peripheral shell around the mitochondrially encoded catalytic core. Despite its size, this subunit is required for stable holoenzyme accumulation, so loss produces isolated complex IV deficiency with reduced cytochrome c oxidase activity and accumulated subassemblies, and de novo human variants have been reported in mitochondrial disease with encephalopathy. The design fork separates absolute requirement, tested by a floxed conditional null, from interface specific questions, tested by transmembrane substitutions that keep the subunit in place and better mimic patient alleles. No isoform paralog covers 7C in somatic tissues. Direct deletion with Nes-Cre, Ckmm-Cre, or inducible Rosa26-CreER, then combine COX histochemistry, spectrophotometric complex IV activity, respirometry, and blue native assembly analysis.
What Cox7c mouse models are available?
ingenious targeting laboratory offers 2 distinct Cox7c (COX7C) catalog mouse models, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Cox7c model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Cox7c allele types
Knockout, conditional, knockin, humanized, and related paths for Cox7c (human COX7C). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Cox7c catalog models
2 Cox7c lines with QC documentation and technical support. Cox7c floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
- Order
Cox7c-Flox
CKOCKO
These mice carry loxP sites flanking exon 1-2 of Cox7c gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cox7c gene.
In production — inquireCKO 262436 - Order
Cox7c-KO
KOKO
The exon1-2 of Cox7c gene was deleted to generate Cox7c knockout mouse.
In DevelopmentKO 262178
Looking for a Cox7c mouse model?
We have 2 Cox7c models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Cox7c Mouse Model Types
A Cox7c knockout mouse has the Cox7c gene permanently inactivated, enabling loss of function studies. A Cox7c conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Cox7c, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Cox7c organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ITL
Send the Cox7c line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.