Conventional / global / constitutive KO
●1 Model Available
READY TO SHIP!
DEVELOPING
Cox8c Knockout mouse model
Browse 1 Cox8c mouse model including knockout variants from ingenious targeting laboratory. Contact us for availability and fast turnaround.
Why model Cox8c
Cox8c, ortholog of human COX8C, encodes a divergent, tissue-restricted paralog of the cytochrome c oxidase subunit 8 family whose expression is confined to a narrow set of tissues and is far lower than that of the ubiquitous Cox8a product, making it a candidate for isoform-specific tuning of complex IV rather than a core structural requirement. Where expressed, the protein is predicted to occupy the same peripheral position on the complex IV monomer as other subunit 8 isoforms, so functional consequences should appear as modest shifts in holoenzyme stability or assembly kinetics rather than as frank deficiency. A constitutive null is usually the correct first experiment here, since baseline phenotypes are poorly characterized and viability is not in question, while reporter-tagged alleles better define genuine expression domains. Given clear redundancy with Cox8a, plan compound alleles if an isoform-null respiratory readout is required, and restrict endpoints to high-resolution respirometry in tissues where Cox8c transcript is actually detectable.
What Cox8c mouse models are available?
ingenious targeting laboratory offers 1 distinct Cox8c (COX8C) catalog mouse model, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 1 Ready Catalog Line | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Cox8c model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Cox8c allele types
Knockout, conditional, knockin, humanized, and related paths for Cox8c (human COX8C). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Cox8c catalog models
1 Cox8c line with QC documentation and technical support.
- Order
Cox8c-KO
KOKO
The exon1-2 of Cox8c gene was deleted to generate Cox8c knockout mouse.
In DevelopmentKO 262240
Looking for a Cox8c mouse model?
We have 1 Cox8c model available — including Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
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Models Available
1
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Cox8c Mouse Model Types
A Cox8c knockout mouse has the Cox8c gene permanently inactivated, enabling loss of function studies.
Modifications available
Jump to catalog backed pages for Cox8c organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ITL
Send the Cox8c line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.