Conventional / global / constitutive KO
●3 Models Available
Wnt6 Conditional Knockout, Knockout mouse models
Browse 3 Wnt6 mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Wnt6 conditional knockout mouse, Wnt6 knockout mouse. Contact us for availability and fast turnaround.
Why model Wnt6
Wnt6 is the mouse ortholog of human WNT6 and encodes a canonical Wnt of epithelial appendage and somite programs, stabilizing beta-catenin through Frizzled with LRP5 or LRP6 in surface ectoderm, where it contributes to dermomyotome specification and myogenic commitment, and in tooth, hair follicle, and placental epithelium. The dominant practical consideration is genomic architecture, since Wnt6 lies immediately adjacent to Wnt10a and the two share regulatory elements, so any targeting strategy must leave neighboring enhancers and the Wnt10a transcription unit intact, otherwise apparent Wnt6 phenotypes reflect collateral regulatory damage. Nulls are viable, so conditional deletion is used mainly to isolate stage-specific ectodermal requirements, reporter or Cre knockins provide lineage access, and humanization supports Porcupine inhibitor pharmacology. Wnt10a and Wnt10b overlap functionally in the same appendage tissues, so compound alleles plus a validated ectodermal driver are appropriate when placode or myogenic endpoints are primary.
What Wnt6 mouse models are available?
ingenious targeting laboratory offers 3 distinct Wnt6 (WNT6) catalog mouse models in the Wnt family, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 3 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Wnt6 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Wnt6 allele types
Knockout, conditional, knockin, humanized, and related paths for Wnt6 (human WNT6). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Wnt6 catalog models
3 Wnt6 lines with QC documentation and technical support. Wnt6 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Wnt6 mouse model?
We have 3 Wnt6 models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model3
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Wnt6 Mouse Model Types
A Wnt6 knockout mouse has the Wnt6 gene permanently inactivated, enabling loss of function studies. A Wnt6 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Wnt6, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Wnt6 organized by modification type. Each URL is indexable and matches common search patterns.