Conventional / global / constitutive KO
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Browse 2 Wnt9b mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Wnt9b conditional knockout mouse, Wnt9b knockout mouse. Contact us for availability and fast turnaround.
Of the two Wnt9 paralogs, Wnt9b, the mouse ortholog of human WNT9B, dominates the urogenital lineage, stabilizing beta-catenin through Frizzled with LRP5 or LRP6, acting from Wolffian and ureteric epithelium as the inductive signal that triggers ureteric bud outgrowth, nephron progenitor induction, and nephric and Mullerian duct elongation, with additional roles in hepatocyte zonation. Nulls lack kidneys and gonaducts and die at birth, so conditional deletion with Hoxb7-Cre or an inducible ureteric driver is the only practical route to later nephrogenesis and duct questions, and dosage-sensitive hypomorphs are valuable because the ligand behaves as a quantitative inducer. The locus also carries the classic cleft lip modifier on the A/WySn background, so regulatory variant knockins address craniofacial risk separately from coding loss, while humanization supports agonist pharmacology. Wnt9a overlaps in kidney induction, making compound conditional alleles worthwhile before concluding a requirement is Wnt9b specific.
ingenious targeting laboratory offers 2 distinct Wnt9b (WNT9B) catalog mouse models in the Wnt family, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
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Knockout, conditional, knockin, humanized, and related paths for Wnt9b (human WNT9B). Catalog lines ship when inventory exists. Everything else is a generation quote.
Specify tissue or Cre driver on quote
Convertible floxed allele pathway
Multi allele / compound knockout project
BAC scale deletion or targeting
LSL or conditional expression knockin
Domain or partial humanization scope
Checkpoint IO humanization when gene is a checkpoint target
Multi humanized / combination IO project
BAC transgenic or large fragment insert
Tamoxifen or dox inducible Cre
Dual recombinase breeding scheme
Flp or FRT derivative allele pairing
Catalog reporter lines not tied to a single gene allele
Specify rat on quote
Specify rabbit on quote
Background substrain on quote
Background strain on quote
2 Wnt9b lines with QC documentation and technical support. Wnt9b floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
We have 2 Wnt9b models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog modelA Wnt9b knockout mouse has the Wnt9b gene permanently inactivated, enabling loss of function studies. A Wnt9b conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Wnt9b, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Jump to catalog backed pages for Wnt9b organized by modification type. Each URL is indexable and matches common search patterns.