Conventional / global / constitutive KO
●2 Models Available
Fgf17 Conditional Knockout, Knockout mouse models
Browse 2 Fgf17 mouse models including conditional knockout, knockout variants — in stock and ready to ship from ingenious targeting laboratory. Available as Fgf17 conditional knockout mouse, Fgf17 knockout mouse. Request a quote within 24 hours.
Why model Fgf17
Fgf17, mouse ortholog of human FGF17, is a member of the FGF8 subfamily and encodes a secreted ligand with strong preference for the c-splice receptors FGFR1c, FGFR2c, FGFR3c, and FGFR4, acting alongside FGF8 at the midbrain-hindbrain isthmic organizer and in the anterior neural ridge to pattern frontal cortex, cerebellar vermis, and rostral telencephalon. Nulls are viable but show hypoplasia of the cerebellar vermis, reduced dorsomedial frontal cortex, and altered social behavior, phenotypes that map cleanly onto region-specific FGF dosage. In humans, heterozygous variants have been reported in Kallmann syndrome and normosmic hypogonadotropic hypogonadism, consistent with GnRH neuron and olfactory placode requirements shared with FGF8 and FGFR1. Because viability permits constitutive deletion, the informative designs are hypomorphic allelic series and compound Fgf8 and Fgf17 alleles that titrate isthmic signal, since these two ligands substantially overlap. Reserve conditional floxed alleles with En1-Cre or Emx1-Cre for questions that separate organizer patterning from later cortical growth endpoints.
What Fgf17 mouse models are available?
ingenious targeting laboratory offers 2 distinct Fgf17 (FGF17) catalog mouse models in the FGF family, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Fgf17 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Fgf17 allele types
Knockout, conditional, knockin, humanized, and related paths for Fgf17 (human FGF17). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Looking for a Fgf17 mouse model?
We have 2 Fgf17 models in stock — including Conditional Knockout, Knockout types. In stock and ready to ship this week. All models come with full QC documentation, health certificates, and dedicated technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Fgf17 Mouse Model Types
A Fgf17 knockout mouse has the Fgf17 gene permanently inactivated, enabling loss of function studies. A Fgf17 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Fgf17, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Fgf17 organized by modification type. Each URL is indexable and matches common search patterns.