Conventional / global / constitutive KO
●2 Models Available
Fgf13 Conditional Knockout, Knockout mouse models
Browse 2 Fgf13 mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Fgf13 conditional knockout mouse, Fgf13 knockout mouse. Contact us for availability and fast turnaround.
Why model Fgf13
Fgf13, mouse ortholog of human FGF13, encodes an intracellular FGF homologous factor whose multiple N-terminal splice isoforms are generated from an X-linked locus and which acts through two distinct nonreceptor mechanisms: docking on the C-terminal tails of voltage-gated sodium channels including NaV1.6 to control inactivation and availability, and direct microtubule binding that stabilizes polymers during neuronal polarization and axon branching. It is also a thermal nociception regulator in sensory neurons and contributes to cardiomyocyte excitability. Human hemizygous loss-of-function variants cause X-linked intellectual disability with epilepsy and febrile seizure susceptibility, which makes patient-derived truncating or missense knockins, together with isoform-specific targeting, more informative than whole-gene deletion. Nulls are viable, permitting conditional floxed alleles with Nestin-Cre, Advillin-Cre, or Myh6-Cre to separate cortical, sensory, and cardiac contributions, and X-linkage requires careful hemizygous versus mosaic female design. Paralogs Fgf11, Fgf12, and Fgf14 share channel partners, so compound alleles clarify which factor sets the excitability endpoint being measured.
What Fgf13 mouse models are available?
ingenious targeting laboratory offers 2 distinct Fgf13 (FGF13) catalog mouse models in the FGF family, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Fgf13 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Fgf13 allele types
Knockout, conditional, knockin, humanized, and related paths for Fgf13 (human FGF13). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Fgf13 catalog models
2 Fgf13 lines with QC documentation and technical support. Fgf13 floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Fgf13 mouse model?
We have 2 Fgf13 models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Fgf13 Mouse Model Types
A Fgf13 knockout mouse has the Fgf13 gene permanently inactivated, enabling loss of function studies. A Fgf13 conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Fgf13, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Fgf13 organized by modification type. Each URL is indexable and matches common search patterns.