Conventional / global / constitutive KO
●2 Models Available
Wnt9a Conditional Knockout, Knockout mouse models
Browse 2 Wnt9a mouse models including conditional knockout, knockout variants from ingenious targeting laboratory. Available as Wnt9a conditional knockout mouse, Wnt9a knockout mouse. Contact us for availability and fast turnaround.
Why model Wnt9a
Wnt9a is the mouse ortholog of human WNT9A and encodes a canonical Wnt that stabilizes beta-catenin through Frizzled with LRP5 or LRP6 and is the principal inducer of synovial joint identity, since ectopic expression converts cartilage toward joint interzone fate while loss permits ectopic chondrogenesis within joints and joint fusion. Beyond the skeleton it acts from stromal niches to support hematopoietic stem cell function and from ureteric epithelium to help initiate the mesenchymal to epithelial transition of nephron progenitors, and nulls die perinatally with renal hypoplasia. Joint-restricted conditional deletion using Gdf5-Cre isolates articular maintenance from renal lethality, gain-of-function knockins test the joint induction model directly, and humanization supports agonist pharmacology, while human WNT9A variants in autopod malformation motivate patient missense alleles. Wnt9b overlaps in kidney and duct programs, so compound conditional alleles are advisable whenever urogenital rather than articular endpoints are primary.
What Wnt9a mouse models are available?
ingenious targeting laboratory offers 2 distinct Wnt9a (WNT9A) catalog mouse models in the Wnt family, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 2 Ready Catalog Lines | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Wnt9a model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Wnt9a allele types
Knockout, conditional, knockin, humanized, and related paths for Wnt9a (human WNT9A). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO (floxed / loxP)
Inducible conditional KO (CreER / tet)
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first (tm1a / IKMC)
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI (GFP, YFP, RFP, mCherry, tdTomato, lacZ, luciferase)
Tag KI (FLAG, HA, Myc, V5)
Conditional KI (e.g. Rosa26 LSL)
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Transgenic
Random integration transgenic
Safe harbor (ROSA26, HPRT, H11, Col1a1)
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre (CreER / tet)
Tamoxifen or dox inducible Cre
Dual recombinase (Cre+Dre / Cre+Flp)
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Reporter knockin (gene specific)
Standalone reporter catalog (lineage tracing, constitutive, dual reporter)
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6 (B6J / B6N)
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Wnt9a catalog models
2 Wnt9a lines with QC documentation and technical support. Wnt9a floxed mice use loxP flanked alleles for Cre dependent tissue specific knockout.
Looking for a Wnt9a mouse model?
We have 2 Wnt9a models available — including Conditional Knockout, Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model2
Models Available
2
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Wnt9a Mouse Model Types
A Wnt9a knockout mouse has the Wnt9a gene permanently inactivated, enabling loss of function studies. A Wnt9a conditional knockout (floxed) mouse carries loxP sites flanking a critical exon of Wnt9a, allowing Cre recombinase dependent deletion in specific tissues or at specific timepoints.
Modifications available
Jump to catalog backed pages for Wnt9a organized by modification type. Each URL is indexable and matches common search patterns.