Conventional / global / constitutive KO
●1 Model Available
READY TO SHIP!
DEVELOPING
Fgf9 Knockout mouse model
Browse 1 Fgf9 mouse model including knockout variants from ingenious targeting laboratory. Contact us for availability and fast turnaround.
Why model Fgf9
Fgf9, mouse ortholog of human FGF9, encodes a secreted ligand that homodimerizes through an N-terminal interface, which occludes part of its heparan sulfate binding surface and thereby extends diffusion range, and it activates FGFR2c, FGFR3c, and FGFR1c with ERK output. Its most decisive role is in gonadal sex determination, where it forms a feedforward loop with SOX9 that antagonizes WNT4 and RSPO1, such that XY nulls undergo male-to-female sex reversal, and it further drives lung mesenchymal proliferation, cerebellar and inner ear development, and intestinal mesenchyme growth. Germline deletion is lethal at birth from lung hypoplasia, so conditional floxed alleles are required for postnatal work, while human heterozygous missense variants that increase dimerization cause multiple synostoses syndrome 3 with elbow and knee fusion, making gain-of-function knockins the correct model for that disease class. Overlap with Fgf16 and Fgf20 at shared c-isoform receptors warrants compound alleles. Match allele to gonadal fate, alveolarization, or joint fusion endpoints.
What Fgf9 mouse models are available?
ingenious targeting laboratory offers 1 distinct Fgf9 (FGF9) catalog mouse model in the FGF family, featuring conditional knockout and standard knockout. Researchers can order pre-developed catalog lines or request a custom mouse model, including humanized, knockin, and transgenic variations with verified germline transmission.
| Model Availability | Allele Class Options |
|---|---|
| 1 Ready Catalog Line | Conditional Knockout (cKO) |
| Custom Model Generation | Constitutive Knockout (KO) |
| Advanced Modifications | Humanized, Knockin, Transgenic |
- Quality Control
- Documented Germline Transmission
- Quality Control
- Strict United States QC Guidelines
- Quality Control
- Cryo or Live Dispatch Options
Fgf9 model types
PathAvailability
Knockout
Conditional knockout
Knockin
Humanized
Transgenic / overexpression
Prefer the order form? Order. Need an allele that is not listed? Request a quote.
Fgf9 allele types
Knockout, conditional, knockin, humanized, and related paths for Fgf9 (human FGF9). Catalog lines ship when inventory exists. Everything else is a generation quote.
Knockout
Conditional KO
Inducible conditional KO
Tissue specific KO
Specify tissue or Cre driver on quote
Knockout first
Convertible floxed allele pathway
Double / compound KO
Multi allele / compound knockout project
Large scale / BAC deletion
BAC scale deletion or targeting
Knockin
Point mutation KI
cDNA KI
Reporter KI
Tag KI
Conditional KI
LSL or conditional expression knockin
Gene replacement KI
Humanized
Full gene replacement
Partial / domain humanized
Domain or partial humanization scope
Immune checkpoint humanized
Checkpoint IO humanization when gene is a checkpoint target
Single humanized
Double / multi humanized
Multi humanized / combination IO project
Targeted Transgenic
Safe harbor
Overexpression transgenic
BAC transgenic
BAC transgenic or large fragment insert
Cre / recombinase
Constitutive Cre driver
Inducible Cre
Tamoxifen or dox inducible Cre
Dual recombinase
Dual recombinase breeding scheme
Flp driver
Flp or FRT derivative allele pairing
Reporter
Gene specific reporter knockin
Standalone reporter catalog
Catalog reporter lines not tied to a single gene allele
Species / background
Rat KO / KI / transgenic
Specify rat on quote
Rabbit models
Specify rabbit on quote
C57BL/6
Background substrain on quote
BALB/c
129, NOD, NSG, FVB, CD1, DBA/2
Background strain on quote
Available Fgf9 catalog models
1 Fgf9 line with QC documentation and technical support.
- Order
Fgf9-KO
KOKO
The exon2 of Fgf9 gene was deleted to generate Fgf9 knockout mouse.
In DevelopmentKO 262247
Looking for a Fgf9 mouse model?
We have 1 Fgf9 model available — including Knockout types. Contact us today for current availability and our fastest turnaround options. All models come with full QC documentation and technical support.
Best pricing in the industry. Get a quote in 24 hours. Our team of PhD scientists is available to help you select the right model for your research.
Order catalog model1
Models Available
1
Model Types
24 hrs
Quote Turnaround
Included
QC Documentation
About Fgf9 Mouse Model Types
A Fgf9 knockout mouse has the Fgf9 gene permanently inactivated, enabling loss of function studies.
Modifications available
Jump to catalog backed pages for Fgf9 organized by modification type. Each URL is indexable and matches common search patterns.
Breed this line with ITL
Send the Fgf9 line to a U.S. barrier facility for colony maintenance, cohort production, and complex breeding schemes through mouse breeding services.